In the thickbox.js, add a line in the tb_remove() function
function tb_remove() {
$("#TB_imageOff").unbind("click");
$("#TB_closeWindowButton").unbind("click");
$("#TB_window").fadeOut("fast",function(){$('#TB_window,#TB_overlay,#TB_HideSelect').trigger("unload").unbind().remove();});
$("#TB_load").remove();
if (typeof document.body.style.maxHeight == "undefined") {//if IE 6
$("body","html").css({height: "auto", width: "auto"});
$("html").css("overflow","");
}
document.onkeydown = "";
document.onkeyup = ""; parent.location.reload(1); // Add this line return false;
}Choice 2 : Click a button to close the thickbox and refresh the parent page
<button onClick="parent.tb_remove(); parent.location.reload(1)">Close It</button>
Taken From : http://jquery.com/demo/thickbox/
Related Links:
Lightbox 2
Fancybox